Human Ovarian Bank
Director: Dr. Bita Ebrahimi
b.ebrahimi@royaninstitute.Org
Dr. Bita Ebrahimi was born in 1975 and graduated from Tehran University of Medical Sciences with a bachelor's degree in physiotherapy in 1998, and she has completed her graduate studies with a master's degree and doctorate in the field of Anatomical Sciences at Tarbiat Modares University. In 2008, she graduated as a distinguished student after completing his doctoral thesis under the guidance of Dr. Mojtabi Rezazadeh. The thesis was titled "Evaluation of maturity and ultrastructure of oocyte-cumulus complexes of sheep after glass freezing with conventional crytop and solid surface methods." She started her collaboration with Royan Institute in 2010 and currently works as a faculty member in the embryology department. Her main research subject is to investigate the processes of freezing and culturing ovarian tissue and the molecular mechanisms involved in them. She has presented about 50 articles in prestigious domestic and foreign magazines, as well as about 90 summaries of articles in prestigious scientific congresses and seminars inside and outside the country.
History
Fortunately, to the continuous advancements in cancer treatments, there has been a notable rise in the number of children who have survived cancer.
The destructive effects of cytotoxic treatments on the gonads cannot be ignored, so the necessity of using assisted reproductive techniques to preserve the fertility of these patients is very important. Embryo, ovum, and ovarian tissue freezing is a technique used to preserve female fertility. Embryo freezing is a highly effective option for preserving fertility, for adults who are married and have sufficient time to stimulate ovulation. If the patient is single, then egg freezing would be the appropriate option. In case of moral obstacles, the impossibility of stimulating ovulation, the urgency of cancer treatments or the person's immaturity, ovarian tissue freezing can be implemented as a new method of helping to preserve fertility. In ovarian tissue freezing, the tissue is a reservoir that has many follicles in different stages of growth and development; It is stored and maintained without any delay in the initiation of cancer treatment. The Embryology Department's Human Ovary Bank tries to freeze and preserve ovarian tissue using the best method. It also tries to optimize the laboratory conditions for growing human tissue and follicles while exploring the various molecular mechanisms that contribute to follicle maturation and development. In 2009, this bank was established as a subgroup of the research embryology department, and currently, in addition to accepting patients, it is also active in research projects.
Goals
Providing medical services to visiting patients to maintain fertility
Optimizing ovarian tissue freezing and preservation methods
Launching different methods of using frozen ovarian tissue, especially ovarian tissue culture and follicular culture after tissue freezing
Freezing of human follicles
Members
Dr. Bita Ebrahimi (Ph.D. in Anatomical Sciences)
Naimeh Sadat Abtahi (Master of Developmental Biology)
Dr. Rouhollah Fathi (specialized doctorate in anatomical sciences)
Dr. Maryam Hazavehei (doctorate in cell-developmental specialization)
b.ebrahimi@royaninstitute.Org
Dr. Bita Ebrahimi was born in 1975 and graduated from Tehran University of Medical Sciences with a bachelor's degree in physiotherapy in 1998, and she has completed her graduate studies with a master's degree and doctorate in the field of Anatomical Sciences at Tarbiat Modares University. In 2008, she graduated as a distinguished student after completing his doctoral thesis under the guidance of Dr. Mojtabi Rezazadeh. The thesis was titled "Evaluation of maturity and ultrastructure of oocyte-cumulus complexes of sheep after glass freezing with conventional crytop and solid surface methods." She started her collaboration with Royan Institute in 2010 and currently works as a faculty member in the embryology department. Her main research subject is to investigate the processes of freezing and culturing ovarian tissue and the molecular mechanisms involved in them. She has presented about 50 articles in prestigious domestic and foreign magazines, as well as about 90 summaries of articles in prestigious scientific congresses and seminars inside and outside the country.
History
Fortunately, to the continuous advancements in cancer treatments, there has been a notable rise in the number of children who have survived cancer.
The destructive effects of cytotoxic treatments on the gonads cannot be ignored, so the necessity of using assisted reproductive techniques to preserve the fertility of these patients is very important. Embryo, ovum, and ovarian tissue freezing is a technique used to preserve female fertility. Embryo freezing is a highly effective option for preserving fertility, for adults who are married and have sufficient time to stimulate ovulation. If the patient is single, then egg freezing would be the appropriate option. In case of moral obstacles, the impossibility of stimulating ovulation, the urgency of cancer treatments or the person's immaturity, ovarian tissue freezing can be implemented as a new method of helping to preserve fertility. In ovarian tissue freezing, the tissue is a reservoir that has many follicles in different stages of growth and development; It is stored and maintained without any delay in the initiation of cancer treatment. The Embryology Department's Human Ovary Bank tries to freeze and preserve ovarian tissue using the best method. It also tries to optimize the laboratory conditions for growing human tissue and follicles while exploring the various molecular mechanisms that contribute to follicle maturation and development. In 2009, this bank was established as a subgroup of the research embryology department, and currently, in addition to accepting patients, it is also active in research projects.
Goals
Providing medical services to visiting patients to maintain fertility
Optimizing ovarian tissue freezing and preservation methods
Launching different methods of using frozen ovarian tissue, especially ovarian tissue culture and follicular culture after tissue freezing
Freezing of human follicles
Members
Dr. Bita Ebrahimi (Ph.D. in Anatomical Sciences)
Naimeh Sadat Abtahi (Master of Developmental Biology)
Dr. Rouhollah Fathi (specialized doctorate in anatomical sciences)
Dr. Maryam Hazavehei (doctorate in cell-developmental specialization)
