Reproductive Clinical Research Laboratory
Reproductive Clinical Research Laboratory operates in two fields of Research, Female Infertility, and Male Infertility, and accepts students with Master's and Doctorate degrees in line with its activity axes. One of the main goals of this laboratory is to identify the cellular and molecular mechanisms involved in fertility, as well as the pathogenesis of male and female infertility, in order to help solve the challenges that come with infertility treatment.
Research plans focused on understanding the cellular and molecular mechanisms of female infertility can be carried out using samples of endometrial tissue, fallopian tubes, follicular fluid, and blood obtained from infertile women. Similarly, for male infertility, research can be conducted using samples of semen, testicular tissue, and blood collected from infertile men. On the other hand, due to the rarity of tissue and sperm samples from some infertile patients using the freezing technique, these samples are stored for cellular and molecular studies.
In general, in the reproduction clinical research laboratory, there are two separate spaces for carrying out cellular research and molecular research, in which applicable techniques include the following:
Research plans focused on understanding the cellular and molecular mechanisms of female infertility can be carried out using samples of endometrial tissue, fallopian tubes, follicular fluid, and blood obtained from infertile women. Similarly, for male infertility, research can be conducted using samples of semen, testicular tissue, and blood collected from infertile men. On the other hand, due to the rarity of tissue and sperm samples from some infertile patients using the freezing technique, these samples are stored for cellular and molecular studies.
In general, in the reproduction clinical research laboratory, there are two separate spaces for carrying out cellular research and molecular research, in which applicable techniques include the following:
- Techniques related to primary cell culture and cell line
- DNA and RNA extraction from tissue and cell samples
- Performing genomic and transcriptomic diagnostic techniques including: PCR, q-PCR, RFLP and PCR array
- Performing protein detection techniques including IHC, ICC and IF staining
- Sperm freezing and performing additional sperm tests including: checking DNA breakage, sperm chromatin maturation, evaluating the amount of ROS and antioxidants
